Gasof 480 mg + 20 mg Chewable Tablet

Gasof 480 mg + 20 mg chewable tablet by Guardian Healthcare Ltd. is a medicine containing Magaldrate + Simethicone. In Bangladesh, it is commonly used for short-term relief of acidity, heartburn, acid indigestion, sour stomach, and bloating or discomfort due to gas.

Magaldrate + Simethicone works by neutralising excess stomach acid with magaldrate and helping break up gas bubbles with simethicone. A key caution is that people with kidney disease, severe or persistent abdominal symptoms, or symptoms such as vomiting blood or black stools should seek medical advice before using it.

• Relief of heartburn, acid indigestion, sour stomach, and symptoms of hyperacidity.
• Symptomatic relief of dyspepsia and gastritis-like burning discomfort where an antacid is appropriate.
• Relief of bloating, fullness, and abdominal discomfort associated with excess gas.
• May be used as supportive symptomatic treatment in gastro-oesophageal reflux or peptic ulcer disease when advised by a healthcare professional.

Adults generally take Magaldrate + Simethicone after meals and at bedtime, or when symptoms occur, according to the product label or the prescriber’s advice. Chewable tablets should be chewed well before swallowing. Suspension should be shaken well before each dose. The exact dose and frequency depend on the strength, formulation, symptoms, and the patient’s medical condition; do not exceed the recommended dose and consult a doctor if regular use is needed for more than a short period.

• Common: constipation, diarrhoea, nausea, stomach cramps, chalky taste, or mild abdominal discomfort.
• Less common: loss of appetite or changes in bowel habit.
• With excessive or prolonged use, especially in kidney disease: high magnesium levels, aluminium accumulation, low phosphate levels, weakness, confusion, bone problems, or worsening kidney-related complications.
• Serious but rare: allergic reaction such as rash, swelling, severe dizziness, or breathing difficulty; seek urgent medical help.

Use caution in people with kidney disease, low blood phosphate, dehydration, bowel obstruction symptoms, chronic diarrhoea or constipation, or in elderly or frail patients. Do not ignore alarm symptoms such as unexplained weight loss, difficulty swallowing, persistent vomiting, severe abdominal pain, vomiting blood, or black stools. Use during childhood should follow medical advice. Use Magaldrate + Simethicone under the guidance of a registered doctor or pharmacist, especially if symptoms are frequent, severe, recurrent, or if other medicines are being taken.

• Antacids can reduce the absorption of many medicines; separate dosing from other medicines as advised, commonly by at least 2–4 hours.
• Important examples include tetracycline and quinolone antibiotics, iron supplements, levothyroxine, bisphosphonates, digoxin, some antifungals, and certain antiviral medicines.
• Taking with citrate-containing products may increase aluminium absorption and should be avoided or discussed with a healthcare professional, especially in kidney disease.
• Alcohol, smoking, very spicy or fatty foods, and large late meals may worsen acidity or reflux symptoms.

• Known hypersensitivity to magaldrate, simethicone, aluminium or magnesium-containing antacids, or any ingredient of the formulation.
• Severe kidney impairment unless specifically directed by a doctor.
• Known or suspected gastrointestinal obstruction, severe abdominal pain of unknown cause, or symptoms suggesting gastrointestinal bleeding without medical assessment.
• Marked low phosphate levels unless advised and monitored by a healthcare professional.

Magaldrate and simethicone have low systemic absorption, and occasional short-term use of antacids is generally considered acceptable during pregnancy or breastfeeding when needed. However, pregnant or breastfeeding women should use the lowest effective amount for the shortest time and seek advice from a doctor or pharmacist, especially if symptoms are frequent, severe, or prolonged.

Store at room temperature, away from excessive heat, direct sunlight, and moisture. Keep the container tightly closed. Do not freeze the suspension and shake well before use. Keep all medicines out of the reach of children.