Capsule
Staphen 250 mg Capsule
Generic: Flucloxacillin
Manufacturer: Synovia Pharma PLC.
Therapeutic class: Penicillinase-resistant penicillin antibiotic
What is Staphen used for?
Staphen (Capsule) contains Flucloxacillin 250 mg and is made by Synovia Pharma PLC. Therapeutic class: Penicillinase-resistant penicillin antibiotic.
What is Staphen?
Staphen 250 mg Capsule contains flucloxacillin, a penicillinase-resistant penicillin antibiotic from Synovia Pharma PLC. It is used for bacterial infections caused by susceptible organisms, especially penicillinase-producing staphylococcal infections such as skin and soft tissue infections.
Staphen 250 mg capsule by Synovia Pharma PLC. contains Flucloxacillin, a penicillin-type antibiotic that is especially effective against staphylococcus ("staph") bacteria. It is mainly used for skin and soft-tissue infections such as cellulitis, infected wounds, boils, and abscesses, as well as some bone, ear, and chest infections. Staphen is a prescription-only medicine and must be taken exactly as a registered doctor instructs.
Flucloxacillin works by breaking down the protective cell wall that bacteria build to survive. Unlike ordinary penicillin, it resists an enzyme (penicillinase) that staph bacteria use to defend themselves, so it can kill these otherwise resistant bacteria. It acts only against bacteria and has no effect on viral illnesses.
Indications
- Skin and soft-tissue infections (cellulitis, boils, abscesses)
- Infected wounds, burns, and insect bites
- Impetigo and other staph skin infections
- Bone and joint infections (often with other treatment)
- Some ear, chest, and surgical-wound infections
Dosage & Administration
ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Staphen 250 mg Capsule. Use the dose your doctor prescribed and the instructions in the pack leaflet.
Side Effects
Flucloxacillin is usually well tolerated. Possible side effects include:
- Nausea, vomiting, or diarrhoea
- Indigestion or abdominal discomfort
- Mild skin rash
- Thrush with longer courses
Rarely, flucloxacillin can cause liver problems (sometimes appearing days or weeks after stopping) with yellowing of the skin or eyes, dark urine, and itching. Seek urgent care for serious allergic reactions, jaundice, or severe, persistent diarrhoea.
Precautions & Warnings
Staphen is a prescription-only antibiotic — never self-medicate. Take it only when a registered doctor prescribes it, and never share it with others or buy it over the counter for a skin problem. Always complete the full course, even after the wound or rash looks healed; the infection can reach deeper than it appears, and stopping early lets resistant bacteria survive and return.
Tell your doctor about any penicillin allergy or past liver problems with this medicine. Antibiotic resistance is a serious national crisis in Bangladesh, and using antibiotics like Flucloxacillin without proper advice or for the wrong reasons makes it worse.
Drug Interactions
Tell your doctor about all medicines you take. Notable interactions with Flucloxacillin include:
- Methotrexate — its toxicity can increase
- Probenecid — raises flucloxacillin levels in the blood
- Warfarin — bleeding tendency may change
- Paracetamol — taken together in high doses long term, a rare blood-acid problem has been reported
- Oral typhoid vaccine may be less effective
Contraindications
Do not take Staphen if you:
- Are allergic to flucloxacillin, penicillin, or related antibiotics
- Have had jaundice or liver problems caused by flucloxacillin before
Use with caution and tell your doctor if you have liver or kidney disease, or are elderly, as the rare risk of liver effects is higher. Your doctor will decide whether Staphen is suitable for you.
Pregnancy & Lactation
Flucloxacillin is generally considered acceptable during pregnancy when needed, as penicillins have a long record of use, but take it only on a doctor's advice. Tell your doctor if you are pregnant or planning to conceive.
Only tiny amounts pass into breast milk and it is usually regarded as compatible with breastfeeding, though the baby may occasionally have loose stools or thrush. Always mention breastfeeding before starting Staphen.
Storage Conditions
Store as printed on the pack and keep out of the reach of children.