Seclo 20 mg Capsule

Seclo 20 mg Capsule contains omeprazole, a proton pump inhibitor from Square Pharmaceuticals PLC. It is used for acid-related conditions such as heartburn, gastroesophageal reflux disease, and stomach or duodenal ulcers.

Seclo 20 mg is Square Pharmaceuticals' omeprazole brand and one of the best-selling anti-ulcer medicines in Bangladesh. As a proton pump inhibitor (PPI), it strongly reduces stomach acid production by blocking the H⁺/K⁺-ATPase enzyme in the stomach lining.

It is used for acidity, heartburn, gastric and duodenal ulcers, and acid reflux disease (GERD).

• Gastro-oesophageal reflux disease (GERD)
• Gastric and duodenal ulcers
• Heartburn and acid dyspepsia
• NSAID-associated ulcer prevention
• Zollinger–Ellison syndrome
• Helicobacter pylori eradication (with antibiotics)

Adults: Usually 20 mg once daily before breakfast. For severe reflux or ulcers, doctors may prescribe 40 mg daily or extend treatment to 4–8 weeks.

Swallow the capsule whole with water — do not crush or chew. Take at least 30–60 minutes before a meal for best effect.

Common side effects are usually mild and temporary:

• Headache
• Diarrhoea or constipation
• Abdominal pain, flatulence
• Nausea

Long-term use may be associated with vitamin B12 deficiency, low magnesium, and a slightly increased risk of bone fracture.

Caution: Long-term, unsupervised use of PPIs is common in Bangladesh but not recommended. If symptoms persist beyond 14 days of self-treatment, see a doctor — persistent symptoms can mask stomach cancer or H. pylori infection. Use the lowest effective dose for the shortest duration.

Omeprazole may interact with:

• Clopidogrel — may reduce its antiplatelet effect
• Diazepam, phenytoin, warfarin — slower elimination
• Ketoconazole, itraconazole — reduced absorption
• Methotrexate — increased levels

Hypersensitivity to omeprazole or other PPIs. Should not be taken together with rilpivirine-containing medicines.

Omeprazole may be used in pregnancy when clearly needed (US FDA category C). Small amounts pass into breast milk; consult your doctor before use while breastfeeding.

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.