Razolam .25 mg Tablet

Razolam .25 mg tablet is manufactured by Renata PLC and contains Alprazolam, a fast-acting benzodiazepine used for the short-term treatment of severe anxiety and panic disorder. Alprazolam is one of the most misused medicines in Bangladesh — it is often taken without prescription as a sleeping pill, which leads quickly to dependence. Razolam should only ever be used under a doctor's close supervision, at the lowest dose, for the shortest time, and never shared with anyone.

Alprazolam works by boosting GABA, the brain's natural calming chemical. This rapidly damps down overactive nerve signalling, easing anxiety and panic within 30–60 minutes — but the same fast, pleasant calming effect is exactly what makes it habit-forming.

Doctors prescribe Razolam for short-term use only in:

• Severe anxiety that is disabling and needs rapid, temporary relief
• Panic disorder — sudden attacks of intense fear with palpitations, sweating and breathlessness — usually while a long-term medicine such as an SSRI starts to work
• Anxiety-related sleep disturbance, briefly and only on medical advice

Razolam is not a routine sleeping pill and not a cure for anxiety. Self-medicating with it is dangerous. Lasting recovery comes from treating the underlying disorder with a psychiatrist's help.

Razolam is strictly prescription-only and should ideally be supervised by a psychiatrist. General information only — your doctor decides your dose and duration:

• Anxiety (adults): commonly 0.25–0.5 mg two to three times daily, adjusted by the doctor.
• Panic disorder: doctors may use higher, carefully titrated doses under close follow-up.
• Elderly: lower doses because of sedation and fall risk.
• Duration: the shortest possible — generally no more than 2–4 weeks including tapering.

Never stop Razolam suddenly after regular use. Abrupt withdrawal can cause severe rebound anxiety, tremor, sleeplessness and even seizures. The dose must be tapered slowly under medical supervision.

Common side effects of Razolam:

• Drowsiness, sedation and daytime sleepiness
• Dizziness, light-headedness, unsteady walking — falls in the elderly
• Poor memory and concentration
• Slurred speech, muscle weakness
• Low mood; occasionally paradoxical agitation or irritability

The most serious risks are dependence and withdrawal: craving, needing higher doses, and severe anxiety, shaking or seizures when stopping suddenly. Overdose — especially mixed with alcohol or opioids — can stop breathing. Get urgent help for extreme drowsiness, confusion, slow or shallow breathing, or if you notice yourself taking more than prescribed.

Critical precautions with Razolam:

• Dependence warning — read carefully: alprazolam is the most misused prescription medicine in Bangladesh. Dependence can develop within a few weeks of regular use. Take it only with a valid prescription, at the exact dose, for the shortest time, and never obtain it from pharmacies without seeing a doctor.
• Never stop abruptly — withdrawal can include seizures; always taper under medical guidance.
• Absolutely no alcohol, and never combine with opioids or other sedatives without your doctor's knowledge — these combinations can be fatal.
• Do not drive or operate machinery while on Razolam.
• Tell your doctor about breathing problems, liver or kidney disease, depression, or any history of alcohol or drug misuse.
• Keep it locked away — never share it.

Tell your doctor everything you take. Dangerous and important interactions with Razolam:

• Alcohol — can fatally suppress breathing; strictly forbidden.
• Opioids (tramadol, codeine, morphine) — combined sedation can be lethal.
• Other sedatives — sleeping pills, sedating antihistamines, antipsychotics, some antidepressants.
• Ketoconazole, itraconazole and similar antifungals — markedly raise Alprazolam levels; combination should be avoided.
• Erythromycin, clarithromycin, some HIV medicines and grapefruit juice — increase its level and effect.
• Carbamazepine, rifampicin — reduce its effect.

Razolam must not be used in:

• Allergy to Alprazolam or other benzodiazepines
• Severe respiratory failure or sleep apnoea syndrome
• Myasthenia gravis
• Severe liver failure
• Together with ketoconazole or itraconazole
• Current untreated alcohol or drug dependence, outside a supervised treatment programme

It is not for children and adolescents, and must not be used as a casual sleep remedy at any age.

Pregnancy: avoid Razolam in pregnancy unless the doctor judges it absolutely essential. Benzodiazepines taken late in pregnancy can leave the newborn floppy, sleepy and feeding poorly, and regular maternal use can cause withdrawal symptoms in the baby. If you become pregnant while taking it, do not stop abruptly — see your doctor promptly for a safe tapering plan.

Breastfeeding: Alprazolam passes into breast milk and may sedate the infant. Breastfeeding is generally not recommended during treatment; discuss safer alternatives with your doctor.

Store Razolam below 30°C in a dry place, away from light and moisture, in its original pack. Because alprazolam is widely misused, keep it locked away, out of the reach of children and of anyone it was not prescribed for. Do not use after the expiry date. Return unused tablets to a pharmacy — never keep leftover strips at home or pass them to friends or relatives.