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Powder For Suspension

Moxaclav 500 mg + 125 mg/5 ml Powder For Suspension

Generic: Amoxicillin + Clavulanic Acid

Manufacturer: Square Pharmaceuticals PLC, Pabna

Therapeutic class: Penicillin + beta-lactamase inhibitor combination antibiotic

What is Moxaclav?

Moxaclav 500 mg + 125 mg/5 ml powder for suspension by Square Pharmaceuticals PLC, Pabna contains Amoxicillin + Clavulanic Acid, a combination antibiotic that pairs a penicillin with a beta-lactamase inhibitor. It is used for bacterial infections that may resist plain amoxicillin, including stubborn chest, sinus, ear, urinary, dental, and skin or soft-tissue infections. Moxaclav is a prescription-only medicine and must be taken exactly as a registered doctor directs.

The amoxicillin part destroys bacteria by breaking down their protective cell wall. Many bacteria fight back by producing an enzyme called beta-lactamase that disables ordinary penicillins; the clavulanic acid in Amoxicillin + Clavulanic Acid blocks this enzyme, allowing the amoxicillin to work against a wider range of resistant bacteria.

Indications

  • Recurrent or resistant ear, nose, and sinus infections
  • Chest infections including some pneumonias and bronchitis flare-ups
  • Urinary tract infections
  • Dental abscesses and gum infections
  • Skin, soft-tissue, and animal/human bite wound infections

Dosage & Administration

The dose of Moxaclav is chosen by the doctor according to the infection and the specific strength of the product. A common adult dose is around one tablet (such as 625 mg) three times daily, or a higher-strength tablet twice daily, for 5 to 7 days. Take Moxaclav at the start of a meal to improve absorption and reduce stomach upset.

Children's doses are based on body weight and the syrup strength, and must be set by a doctor. Complete the whole course, space doses evenly, and do not double up if you miss one.

Side Effects

Side effects are similar to amoxicillin but stomach upset is more common because of the clavulanic acid. They include:

  • Diarrhoea (quite common), nausea, and vomiting
  • Indigestion or abdominal pain
  • Mild skin rash or itching
  • Oral or vaginal thrush with longer courses

Rarely, Amoxicillin + Clavulanic Acid can affect the liver, causing yellowing of the skin or eyes and dark urine. Seek urgent care for severe allergic reactions, persistent or bloody diarrhoea, or signs of liver trouble.

Precautions & Warnings

Moxaclav is a prescription-only antibiotic — never self-medicate. Use it only when a registered doctor prescribes it for your specific infection, and never share it or buy it on your own. Always complete the full course even after you feel well; stopping early lets resistant bacteria survive and the illness return more stubbornly.

Tell your doctor about any penicillin allergy or past liver problems, especially previous jaundice with this medicine. Antibiotic resistance is a serious national crisis in Bangladesh, and misuse of broad combinations like Amoxicillin + Clavulanic Acid accelerates it — reserve it strictly for when a doctor judges it necessary.

Drug Interactions

Inform your doctor about every medicine you take. Important interactions with Amoxicillin + Clavulanic Acid include:

  • Warfarin and other blood thinners — bleeding risk may increase
  • Methotrexate — its toxicity can rise
  • Allopurinol — greater chance of skin rash
  • Probenecid — should not be taken together
  • Oral typhoid vaccine and some other antibiotics

Contraindications

Do not take Moxaclav if you:

  • Are allergic to penicillins, clavulanic acid, or cephalosporins
  • Have had jaundice or liver problems caused by this combination before

Use with caution in people with kidney or liver disease and in glandular fever, where it can cause a rash. Your doctor will weigh these factors before prescribing Moxaclav.

Pregnancy & Lactation

Amoxicillin + Clavulanic Acid is usually considered acceptable in pregnancy when clearly needed, but should be taken only under medical supervision. Let your doctor know if you are pregnant or planning to be, so the safest option can be chosen.

Small amounts pass into breast milk and are generally regarded as compatible with breastfeeding, though the baby may develop loose stools or thrush. Always mention breastfeeding so your doctor can guide you.

Storage Conditions

Store Moxaclav below 25°C in a dry place, away from sunlight, in its original pack. Reconstituted dry syrup should be kept in a refrigerator (do not freeze) and thrown away after the number of days stated on the label. Keep out of reach of children and never use after the expiry date.

Frequently Asked Questions

Moxaclav is giving me loose motions — is this normal and what can I do?

Mild diarrhoea is one of the most common effects of Moxaclav, mainly due to the clavulanic acid. Taking each dose at the start of a meal, drinking plenty of fluids, and eating light meals usually helps. Do not take anti-diarrhoea medicines without asking your doctor. However, if the diarrhoea is severe, watery, contains blood or mucus, or comes with fever and cramps, stop and contact your doctor at once, as this can signal a more serious bowel infection that needs treatment.

My infection cleared in three days — is it safe to stop Moxaclav early?

No. Stopping Moxaclav before the prescribed course is finished is unsafe even when you feel fully recovered. The visible symptoms fade first, but some bacteria remain; ending treatment early lets these hardy survivors regrow and develop resistance, so the next infection may not respond to this or similar antibiotics. Because Amoxicillin + Clavulanic Acid is a powerful combination used for tougher infections, completing it fully matters even more. Antibiotic resistance is a major national crisis in Bangladesh, and finishing every prescribed dose is a simple, vital way to fight it.

How is Moxaclav different from ordinary amoxicillin?

Moxaclav contains amoxicillin plus clavulanic acid. Many bacteria produce an enzyme (beta-lactamase) that destroys plain amoxicillin before it can work; the added clavulanic acid blocks that enzyme, so Moxaclav can treat infections that ordinary amoxicillin cannot. This makes it useful for tougher or recurrent infections, but it is not automatically "better" for every case. Your doctor chooses between them based on the likely bacteria. Using this stronger combination unnecessarily speeds up resistance, so take it only when specifically prescribed.

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