ChamberBD Logo ChamberBD

Tablet

Mirapro 15 Tablet 15 mg Tablet

Generic: Mirtazapine

Manufacturer: Square Pharmaceuticals PLC, Pabna

Therapeutic class: Noradrenergic and Specific Serotonergic Antidepressant (NaSSA)

What is Mirapro 15 Tablet?

Mirapro 15 Tablet 15 mg tablet is manufactured by Square Pharmaceuticals PLC, Pabna and contains Mirtazapine, an antidepressant from the NaSSA group. Because it is sedating and often improves appetite, doctors frequently choose it for people whose depression comes with poor sleep, anxiety at night or loss of appetite and weight. Needing Mirapro 15 Tablet is nothing to feel ashamed of — depression is a real, treatable illness, and taking medicine for it is just as sensible as taking medicine for blood pressure.

Mirtazapine works by increasing the activity of two natural brain chemicals, noradrenaline and serotonin, which help regulate mood, sleep and appetite. Sleep often improves within the first week, while the mood-lifting effect usually takes 2–4 weeks of regular use.

Indications

Doctors prescribe Mirapro 15 Tablet for:

  • Major depression, especially when it comes with insomnia, night-time anxiety or poor appetite and weight loss
  • Depression with prominent anxiety symptoms
  • Sometimes, at the specialist's discretion, for sleep disturbance linked to depression or for patients who could not tolerate SSRI antidepressants

Mirapro 15 Tablet is a prescription-only medicine. Whether it suits your condition, and at what dose, must be decided by a doctor — ideally a psychiatrist — after proper assessment.

Dosage & Administration

Mirapro 15 Tablet is strictly prescription-only; the figures below are general information and your doctor will set your exact dose.

  • Adults: usually started at 15 mg once daily at bedtime, because the medicine is sedating.
  • The dose may be increased gradually to 30–45 mg at night depending on response.
  • Interestingly, lower doses are often more sedating than higher ones — so do not adjust the dose yourself.

Take it every night at the same time. Never stop Mirapro 15 Tablet suddenly: abrupt withdrawal can cause nausea, dizziness, agitation and rebound insomnia. Your doctor will taper the dose slowly when treatment is complete, usually after at least 6 months of feeling well.

Side Effects

Common side effects of Mirapro 15 Tablet include:

  • Drowsiness and sedation, especially in the first weeks — this is why it is taken at night
  • Increased appetite and weight gain — often helpful for underweight patients, but worth monitoring
  • Dry mouth, constipation
  • Dizziness, vivid dreams
  • Mild swelling of hands or feet in some people

See a doctor urgently if you develop fever with sore throat and mouth ulcers (rarely the medicine lowers white blood cells), yellowing of eyes, severe rash, unusual agitation or thoughts of self-harm, particularly in people under 25 during the first weeks of treatment.

Precautions & Warnings

While taking Mirapro 15 Tablet:

  • Use it only under a doctor's supervision and keep all follow-up appointments.
  • Never stop suddenly — the dose must be reduced gradually.
  • Avoid alcohol completely: combined with Mirapro 15 Tablet it causes heavy sedation and worsens depression.
  • Do not drive or operate machinery until you know how sleepy the medicine makes you, especially in the first weeks.
  • Watch your weight and blood sugar if you have diabetes, as appetite may increase.
  • Tell your doctor about epilepsy, heart disease, liver or kidney problems, glaucoma, bipolar disorder or low blood pressure.

Drug Interactions

Tell your doctor about all medicines you use. Key interactions with Mirapro 15 Tablet:

  • MAO inhibitor antidepressants — must not be combined; keep a gap of at least 14 days.
  • Sedatives, sleeping pills and benzodiazepines (e.g., diazepam) — drowsiness is strongly increased.
  • Alcohol — dangerous additive sedation; avoid completely.
  • Other serotonergic drugs — tramadol, triptans, SSRIs, lithium — raise the risk of serotonin syndrome.
  • Carbamazepine and phenytoin may reduce the effect of Mirtazapine, while some antifungals (ketoconazole) and HIV medicines may increase its level.
  • Warfarin — the blood-thinning effect may increase slightly; INR should be monitored.

Contraindications

Mirapro 15 Tablet must not be used if you have:

  • Known allergy to Mirtazapine or any ingredient of the product
  • Current treatment with an MAO inhibitor, or within 14 days of stopping one

It should be used cautiously, under specialist supervision, in people with epilepsy, severe liver or kidney disease, heart rhythm problems, a history of mania or bipolar disorder, glaucoma or a history of low white blood cell counts.

Pregnancy & Lactation

Pregnancy: there is limited experience with Mirtazapine in pregnancy. Mirapro 15 Tablet should be used only if the doctor decides the benefit clearly outweighs the risk — but never stop it on your own, because untreated depression also harms mother and baby. If you are pregnant or planning to be, inform your psychiatrist promptly so the treatment plan can be reviewed.

Breastfeeding: small amounts pass into breast milk. Breastfeeding may be possible under medical supervision; the baby should be watched for excessive sleepiness, poor feeding or poor weight gain. Always take the decision together with your doctor.

Storage Conditions

Store Mirapro 15 Tablet below 30°C in a dry place, protected from light and moisture, in its original packaging. Keep it strictly out of the reach of children. Do not use the medicine after its expiry date, and hand any unused tablets back to a pharmacy rather than discarding them in household rubbish.

Frequently Asked Questions

Why should Mirapro 15 Tablet be taken at night?

<p>Mirapro 15 Tablet is noticeably sedating, especially during the first weeks, so taking it at bedtime turns this side effect into a benefit — it helps you fall asleep while the antidepressant action builds up. Taking it in the morning would leave many people drowsy through the day. Take it at the same time every night, and avoid driving until you know how it affects you the next morning.</p>

Will Mirapro 15 Tablet make me gain weight?

<p>Increased appetite and some weight gain are among the most common effects of Mirapro 15 Tablet. For patients whose depression caused poor appetite and weight loss, this is often helpful. If you are worried about weight, monitor it monthly, choose healthy foods, stay physically active and discuss it at follow-up — your doctor can adjust the plan. Do not stop the medicine on your own because of weight concerns.</p>

Can I stop Mirapro 15 Tablet as soon as my mood improves?

<p>No. Feeling better means the medicine is working — not that the illness is gone. Doctors usually continue treatment for at least 6 months after recovery to prevent relapse. Stopping Mirapro 15 Tablet suddenly can cause nausea, dizziness, anxiety and rebound sleeplessness. When the time comes, your doctor will lower the dose step by step over several weeks. Always decide about stopping together with your doctor.</p>

Was this information helpful?

Last updated: