Flugard 50 mg/5 ml Powder For Suspension

Flugard 50 mg/5 ml powder for suspension contains fluconazole, a triazole antifungal medicine. It is used to treat susceptible fungal infections, including Candida infections of the mouth, throat, genital area, or other body sites.

Flugard 50 mg/5 ml powder for suspension is an antifungal medicine from Pharmasia Ltd. containing Fluconazole. It is prescribed for fungal infections such as vaginal candidiasis (thrush), oral and oesophageal candidiasis, fungal skin infections, and certain serious systemic fungal infections like cryptococcal meningitis. In Bangladesh's hot and humid climate, fungal infections are common, and Flugard is one of the most frequently used oral antifungals.

Fluconazole works by blocking an enzyme fungi need to build ergosterol, an essential part of their cell membrane. Without ergosterol the fungal cell membrane becomes leaky and the fungus cannot grow or survive. Because it is well absorbed by mouth and reaches most body tissues, a single dose is enough for some infections while others need a longer course.

• Vaginal candidiasis (vaginal thrush)
• Oral and oesophageal candidiasis
• Fungal skin infections (tinea/ringworm, pityriasis versicolor)
• Fungal nail infections (onychomycosis)
• Cryptococcal meningitis and other systemic fungal infections
• Prevention of fungal infections in immunocompromised patients

ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Flugard 50 mg/5 ml Powder For Suspension. Use the dose your doctor prescribed and the instructions in the pack leaflet.

Fluconazole is generally well tolerated. Common side effects include nausea, abdominal discomfort, diarrhoea, headache, and skin rash. Less commonly it may alter taste or cause dizziness. Rare but serious effects include liver problems (yellowing of eyes or skin, dark urine, persistent vomiting), severe skin reactions with blistering or peeling, and heart rhythm changes at high doses. Stop the medicine and see a doctor immediately if any of these serious signs appear.

Use fluconazole with caution if you have liver disease, kidney disease, or heart rhythm problems (long QT). Your doctor may adjust the dose in kidney impairment for multi-dose courses. If a rash develops during treatment, report it promptly; stop the drug if the rash spreads or blisters. People with recurrent thrush (four or more episodes a year) should see a doctor to look for underlying causes such as diabetes rather than repeatedly self-treating.

Fluconazole inhibits liver enzymes and raises the levels of many drugs, including warfarin (bleeding risk), phenytoin, sulfonylurea diabetes medicines like glibenclamide and glimepiride (risk of low blood sugar), statins (muscle damage risk), and tacrolimus or ciclosporin. It must not be combined with cisapride, terfenadine, or erythromycin in high doses due to dangerous heart rhythm effects. Rifampicin lowers fluconazole levels. Tell your doctor and pharmacist about every medicine you take.

Fluconazole is contraindicated in people with known allergy to fluconazole or other azole antifungals. It must not be taken with cisapride or terfenadine. Repeated or high-dose use is contraindicated in pregnancy unless a specialist decides otherwise. Significant caution or avoidance applies in severe liver disease and in patients with congenital long QT syndrome.

Pregnancy: Avoid fluconazole in pregnancy, especially repeated or high doses in the first trimester, which have been linked to birth defects and miscarriage risk. For vaginal thrush in pregnancy, doctors usually prefer topical treatments. Lactation: A single 150 mg dose is generally considered compatible with breastfeeding, but longer courses should only be used on a doctor's advice. Always inform your doctor if pregnant or breastfeeding.

Store as printed on the pack and keep out of the reach of children.