Xibast 10 mg Tablet

Xibast 10 is a 10 mg ebastine tablet from Asiatic Laboratories Ltd., in the second-generation non-sedating antihistamine class. It is used to relieve allergy symptoms such as sneezing, runny or itchy nose, and hives.

Xibast 10 10 mg tablet is manufactured by Asiatic Laboratories Ltd.. It contains Ebastine, a second-generation non-sedating antihistamine used to relieve allergy symptoms such as sneezing, runny nose, itchy eyes and hives. Taken once daily, it provides long-lasting relief with little or no drowsiness in most people.

After you take it, Ebastine is converted in the body to its active form, carebastine, which blocks H1 histamine receptors. Histamine is the chemical the body releases during an allergic reaction, and it is responsible for itching, sneezing and watery discharge from the nose and eyes. By preventing histamine from acting, Xibast 10 keeps these symptoms under control for around 24 hours while entering the brain very little, so sedation is uncommon.

Xibast 10 is prescribed for the relief of:

• Allergic rhinitis — seasonal or perennial, with or without allergic conjunctivitis: sneezing, runny and itchy nose, and itchy, watery eyes
• Chronic idiopathic urticaria (long-standing hives) — reducing itching and the number of wheals
• Other itchy allergic skin conditions, as judged by a doctor

Because it is non-sedating in most people, Xibast 10 suits students, drivers and office workers who need allergy relief without daytime sleepiness. Your doctor may also prescribe it for other allergy-related problems not listed here.

ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Xibast 10 mg Tablet. Use the dose your doctor prescribed and the instructions in the pack leaflet.

Most people tolerate Xibast 10 well. Reported side effects include:

• Headache (the most common)
• Dry mouth
• Drowsiness or fatigue (uncommon)
• Abdominal discomfort or indigestion
• Sore throat or runny nose
• Rarely — palpitations or a fast heartbeat

Seek medical help urgently if you develop swelling of the face or throat, breathing difficulty, severe rash, fainting, or a pounding or irregular heartbeat. Tell your doctor if any side effect continues or bothers you while taking Xibast 10.

• Tell your doctor if you have a heart rhythm disorder, a prolonged QT interval, a slow heartbeat or low blood potassium — ebastine combined with certain medicines can affect heart rhythm
• Inform your doctor about liver or kidney disease — the dose may need limiting
• Stop the medicine at least 48–72 hours before allergy skin testing, as it can mask the results
• See how Xibast 10 affects you before driving — a small number of people feel drowsy
• Avoid alcohol, which can add to any sleepiness
• Use in children only at doses set by the doctor

Some medicines can raise the blood level of ebastine and increase the chance of heart-rhythm side effects. Tell your doctor before combining Xibast 10 with:

• Azole antifungals — ketoconazole, itraconazole
• Macrolide antibiotics — erythromycin, clarithromycin
• Other QT-prolonging medicines — certain antiarrhythmics, antipsychotics and antimalarials

Rifampicin may reduce the effect of ebastine. Also mention any sedatives or sleeping pills you use, and limit alcohol. Always share your full medicine list, including herbal and over-the-counter products, with your doctor or pharmacist before starting Xibast 10.

Do not take Xibast 10 if you:

• Are allergic to ebastine or any ingredient of the preparation
• Have a known significant QT-interval prolongation, or take medicines that strongly prolong the QT interval, unless your doctor specifically approves

Use only with a doctor's guidance in severe liver impairment, significant electrolyte disturbance such as low potassium, pregnancy and breastfeeding, and in young children. If you are unsure whether Xibast 10 is right for you, ask your doctor or pharmacist before taking it.

Pregnancy: There is limited information on ebastine use in human pregnancy, so it is generally avoided unless the doctor judges that the benefit outweighs any risk. If you are pregnant or planning a pregnancy, tell your doctor before taking Xibast 10 — an antihistamine with a longer safety record may be preferred.

Breastfeeding: It is not known how much ebastine passes into breast milk, so use it during breastfeeding only on a doctor's advice. If your doctor approves it, watch the baby for unusual sleepiness or poor feeding and report any concern promptly.

Store as printed on the pack and keep out of the reach of children.