Uroflo 400 mcg Capsule

Uroflo 400 mcg Capsule contains tamsulosin hydrochloride, an alpha-1A blocker used in adult men. It is prescribed for urinary symptoms of benign prostatic hyperplasia, such as difficulty starting urination, weak flow, or frequent urination.

Uroflo 400 mcg capsule is manufactured by Beximco Pharmaceuticals Ltd. and contains Tamsulosin Hydrochloride, a selective alpha-blocker used in men. It relieves the urinary symptoms caused by an enlarged prostate gland — a very common condition in men over 50 known as benign prostatic hyperplasia (BPH).

Tamsulosin Hydrochloride works by relaxing the smooth muscle in the prostate and at the neck of the bladder. As the enlarged prostate squeezes the urine passage less tightly, urine flows more easily — so a weak stream, straining, dribbling, incomplete emptying and repeated night-time urination improve, often within one to two weeks. It does not shrink the prostate itself and it is not a treatment for prostate cancer.

Uroflo is prescribed for adult men to relieve the lower urinary tract symptoms of benign prostatic hyperplasia (BPH): weak or interrupted stream, difficulty starting urination, straining, dribbling, a feeling of incomplete emptying, and frequent or urgent urination including at night. Doctors may also use it short term to help small kidney or ureteric stones pass.

Before starting, your doctor may examine the prostate and check urine, kidney function or PSA to make sure the symptoms are not caused by infection, stricture or prostate cancer, which can feel similar. Uroflo is not indicated for women or children.

ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Uroflo 400 mcg Capsule. Use the dose your doctor prescribed and the instructions in the pack leaflet.

Possible side effects of Uroflo include:

• Dizziness or light-headedness, especially on standing up quickly or after the first doses
• Headache, weakness, runny or blocked nose
• Abnormal ejaculation — reduced semen or semen flowing backwards into the bladder (retrograde ejaculation); harmless and reversible, but it can persist while on the medicine
• Palpitations, mild stomach upset, skin rash or itching

Rare but important: fainting, severe allergic swelling of the face or throat, and a prolonged painful erection (priapism), which is an emergency. If you faint, develop chest pain or an allergic reaction, stop the medicine and seek medical care immediately.

Take these precautions with Uroflo:

• Rise slowly from sitting or lying, especially in hot weather, after long standing or if you also take blood pressure medicine; sit or lie down at the first hint of dizziness.
• Avoid driving or operating machinery until you know how the medicine affects you.
• Cataract or glaucoma surgery planned? Tell the eye surgeon that you take — or have ever taken — Uroflo. It can cause floppy iris syndrome during surgery, and the surgeon will adapt the technique.
• Tell your doctor about severe kidney or liver disease, or previous fainting episodes.
• If symptoms do not improve after a few weeks, or urine stops completely, see your doctor promptly.

Tell your doctor and pharmacist about every medicine you take. Key interactions of Uroflo:

• Other alpha-blockers (doxazosin, prazosin, alfuzosin) — do not combine; blood pressure can fall sharply.
• Blood pressure medicines — combined use can cause light-headedness, especially when starting.
• PDE5 inhibitors for erectile dysfunction (sildenafil, tadalafil, vardenafil) — can add to the blood-pressure-lowering effect; ask your doctor about safe timing.
• Strong CYP3A4 inhibitors such as ketoconazole, and to a lesser extent erythromycin or cimetidine — can raise tamsulosin levels.
• Diuretics (water tablets) can worsen dizziness on standing.

Do not take Uroflo if:

• You are allergic to Tamsulosin Hydrochloride or any other ingredient, including previous swelling of the face or throat (angioedema) with it
• You have a history of orthostatic hypotension — fainting or near-fainting when standing up
• You have severe liver failure

Uroflo is not for women — including during pregnancy or breastfeeding — and not for children. It should not be combined with other alpha-blockers, and it should be reviewed before planned cataract surgery. If you have ever fainted after taking a similar medicine, tell your doctor before starting.

Uroflo is a medicine for adult men with prostate enlargement, so the question of use in pregnancy or breastfeeding does not normally arise — it is not indicated for women at all. Studies in men show it can affect ejaculation (reduced or retrograde semen flow), which reverses after stopping.

If a woman — pregnant, breastfeeding or otherwise — takes this medicine by mistake, no serious harm is expected from a single dose, but she should contact a doctor or pharmacist for advice. Keep the capsule well out of reach of children, in whom accidental ingestion can cause dizziness and low blood pressure.

Store Uroflo below 30°C in a cool, dry place, away from direct sunlight and moisture. Keep the capsule in its original blister or container until use — the modified-release coating is sensitive to humidity — and avoid storing it in the bathroom or kitchen.

• Keep all medicines out of the reach and sight of children.
• Do not use the medicine after the expiry date printed on the pack.
• Do not throw unused medicine into household waste or drains; ask your pharmacist about safe disposal.