Capsule
Unibac 400 Capsule 400 mg Capsule
Generic: Cefixime
Manufacturer: OSL Pharma Ltd.
Therapeutic class: Third-generation cephalosporin antibiotic
What is Unibac 400 Capsule?
Unibac 400 Capsule contains cefixime, a third-generation cephalosporin antibiotic used for infections caused by susceptible bacteria. Doctors may prescribe it for conditions such as respiratory tract, urinary tract, ear, throat, or certain sexually transmitted bacterial infections.
Unibac 400 Capsule 400 mg capsule by OSL Pharma Ltd. contains Cefixime, an oral third-generation cephalosporin antibiotic. It is prescribed for a range of bacterial infections such as those of the urinary tract, ear, throat, sinuses, and chest, and is also used in the treatment of typhoid fever when a doctor decides it is appropriate. Unibac 400 Capsule is a prescription-only medicine and must be taken exactly as your registered doctor instructs.
Cefixime works by interfering with the building of the bacterial cell wall. Bacteria need a strong wall to survive; when Cefixime weakens it, the wall collapses and the bacteria die. Like other antibiotics, it is active only against bacteria and has no effect on viral illnesses such as colds, flu, or most coughs.
Indications
- Urinary tract infections
- Ear infections (otitis media)
- Throat and tonsil infections
- Sinusitis and certain chest infections
- Typhoid fever, when chosen by the doctor
- Some sexually transmitted infections (e.g. uncomplicated gonorrhoea)
Dosage & Administration
The dose of Unibac 400 Capsule depends on the infection. A usual adult dose is 200-400 mg daily, taken as a single dose or split into two, for about 7 days; typhoid fever often needs a longer course of one to two weeks as decided by the doctor. Unibac 400 Capsule can be taken with or without food, though food may ease any stomach upset.
Children's doses are based on body weight and must be set by a doctor. Take Unibac 400 Capsule at evenly spaced times, finish the whole course, and do not stop early even if the fever settles quickly.
Side Effects
Cefixime is usually well tolerated. Common side effects include:
- Diarrhoea, nausea, or abdominal pain
- Indigestion or flatulence
- Headache or dizziness
- Mild skin rash
Less commonly it can cause thrush, and rarely it may trigger serious allergic reactions or severe, persistent diarrhoea due to a bowel infection. Seek urgent medical care if you develop facial swelling, breathing difficulty, a spreading rash, or bloody diarrhoea while taking Unibac 400 Capsule.
Precautions & Warnings
Unibac 400 Capsule is a prescription-only antibiotic — never self-medicate. Take it only when a registered doctor prescribes it, and never buy it over the counter or share it with others. Always complete the full prescribed course even after you feel well; in illnesses like typhoid the fever can settle long before the bacteria are fully cleared, and stopping early invites relapse and resistance.
Tell your doctor about any allergy to penicillin or cephalosporins and about kidney disease. Antibiotic resistance is a serious national crisis in Bangladesh, and using cephalosporins like Cefixime unnecessarily makes future infections harder to treat for everyone.
Drug Interactions
Tell your doctor about all medicines and supplements you take. Notable interactions with Cefixime include:
- Warfarin and other blood thinners — bleeding tendency may increase
- Probenecid — raises cefixime levels in the blood
- Carbamazepine — its levels may rise
- Some other antibiotics taken together may reduce effect
- Live oral typhoid vaccine may be less effective
Contraindications
Do not take Unibac 400 Capsule if you:
- Are allergic to cefixime or other cephalosporin antibiotics
- Have had a severe allergic reaction (such as swelling or breathing difficulty) to penicillin
Use with caution and inform your doctor if you have kidney disease, a history of bowel disease (colitis), or a tendency to allergies. Your doctor will decide whether Unibac 400 Capsule is suitable.
Pregnancy & Lactation
Cefixime may be used in pregnancy when the doctor considers it necessary, as cephalosporins are generally regarded as among the safer antibiotic options. Always tell your doctor if you are pregnant or planning to conceive.
Only small amounts pass into breast milk and it is usually considered compatible with breastfeeding, but watch the baby for loose stools or thrush. Discuss breastfeeding with your doctor before taking Unibac 400 Capsule.
Storage Conditions
Store Unibac 400 Capsule in a cool, dry place below 30°C, away from direct sunlight and moisture, in its original pack. Reconstituted suspension for children should be used within the period stated on the label. Keep all forms out of the reach of children and do not use the medicine beyond its expiry date.
Frequently Asked Questions
My doctor prescribed Unibac 400 Capsule for typhoid — why must I keep taking it after the fever drops?
Can I stop Unibac 400 Capsule once I feel completely fine?
Should I take Unibac 400 Capsule with food, and is it safe if I am allergic to penicillin?
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