Thiobion 100 mg Tablet

Thiobion 100 mg tablet by Aristopharma Limited is a medicine containing Thiamine Hydrochloride. In Bangladesh, it is mainly used to prevent or treat vitamin B1 deficiency, including deficiency related to poor nutrition, chronic alcohol use, or conditions such as beriberi and Wernicke’s encephalopathy.

Thiamine Hydrochloride works by replacing thiamine, an essential vitamin needed for carbohydrate metabolism and normal nerve, heart, and brain function. A key caution is that injectable thiamine can rarely cause serious allergic reactions, so injections should be given only with appropriate medical supervision.

• Prevention and treatment of thiamine deficiency.
• Treatment of beriberi due to vitamin B1 deficiency.
• Treatment or prevention of Wernicke’s encephalopathy in patients at risk, such as those with chronic alcohol use or severe malnutrition.
• Supplementation when dietary intake is inadequate or requirements are increased, as advised by a healthcare professional.

Adult dose, route, and duration depend on the reason for use and the severity of deficiency. Tablets are commonly used for prevention or mild deficiency, while injection is reserved for severe deficiency, vomiting, poor absorption, or urgent situations such as suspected Wernicke’s encephalopathy. Follow the prescribed schedule exactly; do not self-inject or change the dose without medical advice.

• Usually well tolerated when taken by mouth.
• Mild stomach upset, nausea, or discomfort may occur.
• Itching, rash, sweating, or flushing may occur rarely.
• Injection may cause pain, redness, or swelling at the injection site.
• Serious allergic reaction, including anaphylaxis, is rare but possible, especially with injection; seek urgent medical help for breathing difficulty, facial swelling, severe dizziness, or widespread rash.

Use with care in anyone with a history of allergy to thiamine, vitamin injections, or any component of the product. Injectable thiamine should be administered where treatment for severe allergic reactions is available. People with chronic alcohol use, malnutrition, liver disease, persistent vomiting, or suspected Wernicke’s encephalopathy should seek medical assessment rather than self-treating. Use under the guidance of a registered doctor or pharmacist.

• Alcohol can reduce thiamine absorption and storage and may worsen deficiency.
• Loop diuretics such as furosemide may increase urinary thiamine loss with long-term use.
• Fluorouracil may interfere with thiamine activation and can contribute to deficiency in some patients.
• Tell your doctor or pharmacist about all medicines, supplements, and herbal products you use.

• Known hypersensitivity to thiamine hydrochloride or any ingredient of the product.
• Previous serious allergic reaction to thiamine injection unless a specialist decides it is essential and appropriate precautions are in place.

Thiamine is an essential vitamin and normal recommended intake is considered safe during pregnancy and breastfeeding. Higher therapeutic doses should be used only when prescribed, particularly if deficiency is suspected or confirmed. Pregnant or breastfeeding women should consult a healthcare professional before using injectable or high-dose thiamine.

Store tablets in a cool, dry place away from direct light and moisture. Store injections as directed on the label, protect from light, and do not use if the solution is discoloured, cloudy, or the container is damaged. Keep all medicines out of the reach of children.