Silagra 25 mg Tablet

Silagra 25 25 mg tablet by Incepta Pharmaceuticals Ltd. is a medicine available in Bangladesh that contains Sildenafil. It is mainly used for the treatment of erectile dysfunction in adult men, when prescribed by a healthcare professional.

Sildenafil works by inhibiting phosphodiesterase type 5 (PDE5), which helps relax blood vessels and improve blood flow in certain parts of the body. A key caution is that it must not be taken with nitrate medicines or riociguat because this can cause a dangerous fall in blood pressure.

• Erectile dysfunction in adult men.
• Pulmonary arterial hypertension, when a sildenafil product and dose are specifically prescribed for this condition.

ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Silagra 25 mg Tablet. Use the dose your doctor prescribed and the instructions in the pack leaflet.

• Common side effects may include headache, flushing, indigestion, nasal congestion, dizziness, nausea, and visual disturbances such as a blue tinge or blurred vision.
• Serious effects needing urgent medical help include chest pain, fainting, severe dizziness, sudden loss of vision, sudden decrease or loss of hearing, allergic reaction, or an erection lasting more than 4 hours.

Use sildenafil with caution in people with heart disease, low or uncontrolled high blood pressure, a history of stroke or heart attack, liver or severe kidney disease, bleeding disorders, stomach ulcer, penile deformity, conditions predisposing to priapism such as sickle cell disease, leukemia or multiple myeloma, or eye conditions such as retinitis pigmentosa or previous non-arteritic anterior ischemic optic neuropathy. Sexual activity may not be advisable for some heart patients; medical assessment is important. Use this medicine only under the guidance of a registered doctor or pharmacist.

• Nitrates such as nitroglycerin, isosorbide dinitrate, or isosorbide mononitrate: contraindicated due to risk of severe hypotension.
• Riociguat: contraindicated due to risk of severe hypotension.
• Alpha-blockers and other blood pressure-lowering medicines: may increase dizziness or low blood pressure.
• Strong CYP3A4 inhibitors such as ritonavir, cobicistat, ketoconazole, itraconazole, clarithromycin, and some other HIV or antifungal medicines can increase sildenafil levels and side effects.
• CYP3A4 inducers such as rifampicin may reduce sildenafil effect.
• Grapefruit or grapefruit juice may increase sildenafil exposure and side effects.
• Alcohol can worsen dizziness, low blood pressure, and erectile dysfunction.
• Do not combine with other PDE5 inhibitors or other erectile dysfunction medicines unless specifically advised by a doctor.

• Known hypersensitivity to sildenafil or any component of the product.
• Use with any nitrate medicine or nitric oxide donor, whether regular or intermittent.
• Use with riociguat.
• Use in patients for whom sexual activity is medically inadvisable because of significant cardiovascular risk, unless cleared by a doctor.

Sildenafil for erectile dysfunction is not intended for use in women. For pulmonary arterial hypertension, use during pregnancy or breastfeeding only if clearly prescribed by a specialist after weighing benefits and risks. Small amounts may pass into breast milk; breastfeeding patients should seek medical advice before use.

Store tablets at room temperature, away from excess heat, moisture, and direct light. Keep in the original packaging, out of the reach of children, and do not use after the expiry date.