R-Saline 6.75 gm + 750 mg + 1.3 gm + 1.45 gm/500 ml Oral Saline

R-Saline 6.75 gm + 750 mg + 1.3 gm + 1.45 gm/500 ml oral saline by Rephco Pharmaceuticals Ltd. is an oral rehydration salt preparation containing Dextrose Anhydrous + Potassium Chloride + Sodium Chloride + Trisodium Citrate. In Bangladesh, it is mainly used to replace water and electrolytes lost during acute diarrhoea and to help prevent dehydration.

Dextrose Anhydrous + Potassium Chloride + Sodium Chloride + Trisodium Citrate works by using glucose to improve intestinal absorption of sodium and water, while potassium, chloride and citrate help correct electrolyte and acid-base losses. A key caution is that it must be mixed with the exact amount of clean water stated on the packet; too little or too much water can be harmful.

• Prevention and treatment of mild to moderate dehydration due to acute diarrhoea.
• Replacement of fluid and electrolyte losses in diarrhoeal illness, including cholera, when the person can drink.
• Supportive rehydration during vomiting or gastroenteritis when oral intake is possible, as advised by a healthcare professional.

Dissolve the whole contents of one sachet in the exact volume of safe drinking water specified on the product label, and use the prepared solution within the recommended time. Adults should sip the solution frequently and drink according to thirst and ongoing fluid loss, especially after each loose stool. Do not use a concentrated or partially mixed sachet. Specific amounts for children, elderly people, pregnancy, severe illness, or ongoing vomiting should be directed by a registered doctor or pharmacist.

• Nausea, mild vomiting, abdominal fullness or bloating may occur, especially if taken too quickly.
• Incorrect mixing or excessive intake may cause high sodium levels, high potassium levels, thirst, weakness, confusion, swelling, or worsening dehydration.
• People with kidney, heart, or fluid-balance problems may develop fluid overload or electrolyte disturbances.
• Seek urgent medical help if there is severe dehydration, inability to drink, persistent vomiting, blood in stool, high fever, reduced urination, drowsiness, or worsening symptoms.

Use with caution in people with kidney disease, reduced urine output, heart failure, high blood pressure requiring salt restriction, diabetes, severe vomiting, suspected intestinal obstruction, or those taking medicines that affect potassium or sodium balance. It is not a substitute for urgent medical care in severe dehydration or shock. Use under a registered doctor's or pharmacist's guidance.

• Potassium-sparing diuretics, ACE inhibitors, angiotensin receptor blockers, aliskiren, potassium supplements, or potassium-containing salt substitutes may increase the risk of high potassium levels.
• Medicines affected by sodium or fluid balance, such as lithium, may require medical monitoring.
• Diuretics and medicines affecting kidney function may increase the risk of electrolyte imbalance.
• Do not mix the powder with milk, juice, soft drinks, or extra sugar or salt; prepare only with the specified amount of clean water.

• Known hypersensitivity to any component of the preparation.
• Severe dehydration with shock, unconsciousness, or inability to drink, where urgent intravenous fluids are required.
• Severe kidney failure with very low or no urine output, unless specifically directed by a doctor.
• Known high potassium or high sodium levels unless medically supervised.
• Suspected intestinal obstruction or ileus.

Oral rehydration salts are generally considered safe during pregnancy and breastfeeding when prepared correctly and used for appropriate fluid replacement. Pregnant or breastfeeding women with severe diarrhoea, persistent vomiting, fever, blood in stool, reduced urination, or signs of dehydration should seek medical care promptly.

Store unopened sachets in a cool, dry place away from moisture, heat, and direct sunlight. Keep out of the reach of children. After mixing, keep the solution covered and use within the time stated on the label; discard any leftover solution after that period.