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Tablet

Prioxim 400 mg Tablet

Generic: Cefixime

Manufacturer: DBL Pharmaceuticals Limited

Therapeutic class: Third-generation cephalosporin antibiotic

What is Prioxim 400 used for?

Prioxim 400 (Tablet) contains Cefixime 400 mg and is made by DBL Pharmaceuticals Limited. Therapeutic class: Third-generation cephalosporin antibiotic.

What is Prioxim 400?

Prioxim 400 is a tablet containing cefixime 400 mg, a third-generation cephalosporin antibiotic from DBL Pharmaceuticals Limited. It is used for susceptible bacterial infections, including infections of the respiratory tract, urinary tract, ear, throat, and some sexually transmitted infections.

Prioxim 400 400 mg tablet by DBL Pharmaceuticals Limited contains Cefixime, an oral third-generation cephalosporin antibiotic. It is prescribed for a range of bacterial infections such as those of the urinary tract, ear, throat, sinuses, and chest, and is also used in the treatment of typhoid fever when a doctor decides it is appropriate. Prioxim 400 is a prescription-only medicine and must be taken exactly as your registered doctor instructs.

Cefixime works by interfering with the building of the bacterial cell wall. Bacteria need a strong wall to survive; when Cefixime weakens it, the wall collapses and the bacteria die. Like other antibiotics, it is active only against bacteria and has no effect on viral illnesses such as colds, flu, or most coughs.

Indications

  • Urinary tract infections
  • Ear infections (otitis media)
  • Throat and tonsil infections
  • Sinusitis and certain chest infections
  • Typhoid fever, when chosen by the doctor
  • Some sexually transmitted infections (e.g. uncomplicated gonorrhoea)

Dosage & Administration

ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Prioxim 400 mg Tablet. Use the dose your doctor prescribed and the instructions in the pack leaflet.

Side Effects

Cefixime is usually well tolerated. Common side effects include:

  • Diarrhoea, nausea, or abdominal pain
  • Indigestion or flatulence
  • Headache or dizziness
  • Mild skin rash

Less commonly it can cause thrush, and rarely it may trigger serious allergic reactions or severe, persistent diarrhoea due to a bowel infection. Seek urgent medical care if you develop facial swelling, breathing difficulty, a spreading rash, or bloody diarrhoea while taking Prioxim 400.

Precautions & Warnings

Prioxim 400 is a prescription-only antibiotic — never self-medicate. Take it only when a registered doctor prescribes it, and never buy it over the counter or share it with others. Always complete the full prescribed course even after you feel well; in illnesses like typhoid the fever can settle long before the bacteria are fully cleared, and stopping early invites relapse and resistance.

Tell your doctor about any allergy to penicillin or cephalosporins and about kidney disease. Antibiotic resistance is a serious national crisis in Bangladesh, and using cephalosporins like Cefixime unnecessarily makes future infections harder to treat for everyone.

Drug Interactions

Tell your doctor about all medicines and supplements you take. Notable interactions with Cefixime include:

  • Warfarin and other blood thinners — bleeding tendency may increase
  • Probenecid — raises cefixime levels in the blood
  • Carbamazepine — its levels may rise
  • Some other antibiotics taken together may reduce effect
  • Live oral typhoid vaccine may be less effective

Contraindications

Do not take Prioxim 400 if you:

  • Are allergic to cefixime or other cephalosporin antibiotics
  • Have had a severe allergic reaction (such as swelling or breathing difficulty) to penicillin

Use with caution and inform your doctor if you have kidney disease, a history of bowel disease (colitis), or a tendency to allergies. Your doctor will decide whether Prioxim 400 is suitable.

Pregnancy & Lactation

Cefixime may be used in pregnancy when the doctor considers it necessary, as cephalosporins are generally regarded as among the safer antibiotic options. Always tell your doctor if you are pregnant or planning to conceive.

Only small amounts pass into breast milk and it is usually considered compatible with breastfeeding, but watch the baby for loose stools or thrush. Discuss breastfeeding with your doctor before taking Prioxim 400.

Storage Conditions

Store as printed on the pack and keep out of the reach of children.

Frequently Asked Questions

Can I stop Prioxim 400 once I feel completely fine?

No. Feeling fine means your symptoms have improved, not that every bacterium is gone. Stopping Prioxim 400 early leaves behind the strongest bacteria, which can multiply and become resistant to cefixime and related antibiotics. The infection may then return in a form that is much harder to cure. Antibiotic resistance is a serious and growing national crisis in Bangladesh. Completing the full course exactly as your doctor prescribed — not stopping when you feel better — is one of the most effective ways to fight it.

Should I take Prioxim 400 with food, and is it safe if I am allergic to penicillin?

Prioxim 400 can be taken with or without food, but taking it with a meal can reduce stomach upset; try to take it at the same times each day. Cefixime is a cephalosporin, which is chemically related to penicillin, so a small number of people allergic to penicillin may also react to it. If you have ever had a serious reaction to penicillin — such as swelling or breathing difficulty — tell your doctor before taking Prioxim 400, as a different antibiotic may be safer.

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