Navix 75 mg Tablet

Navix 75 mg Tablet contains clopidogrel, an antiplatelet medicine that helps stop blood platelets from sticking together. It is used to lower the risk of harmful blood clots in people with conditions such as heart attack, stroke, or peripheral artery disease.

Navix 75 mg tablet is a medicine from Navana Pharmaceuticals Ltd. that contains Clopidogrel, an antiplatelet agent used to prevent dangerous blood clots in people who have had a heart attack, stroke, or a heart stent placed, and in those with blocked leg arteries.

Clopidogrel works on platelets — the tiny blood cells that clump together to form clots. It permanently blocks a receptor (P2Y12) on the platelet surface, so platelets become less sticky and cannot easily clump inside narrowed or stented arteries. This keeps blood flowing to the heart, brain and limbs. Because the effect lasts for the life of each platelet, the medicine keeps protecting you even between doses.

• After a heart attack (myocardial infarction) — to prevent another attack
• After coronary stent placement (PCI/ring) — to stop clots forming inside the stent, usually with aspirin
• Acute coronary syndrome — unstable angina or heart attack, with aspirin
• After ischaemic stroke or mini-stroke (TIA) — to prevent another stroke
• Peripheral arterial disease — blocked leg arteries causing pain on walking

ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Navix 75 mg Tablet. Use the dose your doctor prescribed and the instructions in the pack leaflet.

Because clopidogrel reduces clotting, bleeding-related effects are the most common:

• Bruising more easily, longer bleeding from cuts
• Nosebleeds, bleeding gums
• Stomach upset, diarrhoea, abdominal pain
• Rash or itching

Seek urgent medical help if you notice:

• Black or tarry stools, blood in vomit (may look like coffee grounds), blood in urine
• Unusual or prolonged bleeding that will not stop
• Sudden weakness, severe headache or confusion
• Unexplained fever, extreme tiredness, purple skin spots or yellowing of eyes (very rare blood disorder TTP)

• Tell every doctor, dentist or surgeon that you take Navix before any procedure, surgery or tooth extraction — it is usually stopped 5–7 days beforehand, but only on the prescribing doctor's instruction.
• Tell your doctor if you have a stomach ulcer, previous bleeding, liver disease or a planned operation.
• Use a soft toothbrush and shave carefully to reduce bleeding.
• Avoid contact sports or activities with high injury risk.
• Do not take regular painkillers like ibuprofen or diclofenac without asking — they increase bleeding risk.
• Some people genetically respond less to clopidogrel; if a clot occurs despite the medicine, your doctor may switch to an alternative.

• Omeprazole and esomeprazole (PPIs): can reduce the activation and effect of clopidogrel — doctors usually prefer pantoprazole or rabeprazole if a gastric medicine is needed
• NSAID painkillers (ibuprofen, diclofenac, naproxen) and aspirin: higher bleeding risk; aspirin is combined only when the doctor prescribes it deliberately
• Anticoagulants (warfarin, rivaroxaban, heparin): major bleeding risk — combined only under specialist supervision
• SSRIs (escitalopram, sertraline): can add to bleeding tendency
• Strong CYP2C19 inhibitors (fluconazole, fluoxetine): may blunt clopidogrel's effect

Tell your doctor about all medicines, supplements and herbal products you use.

• Allergy to clopidogrel or any component of the medicine
• Active bleeding — such as a bleeding stomach ulcer or bleeding inside the brain
• Severe liver disease
• It should not be started without medical assessment in people with recent major trauma or surgery

Pregnancy: Clopidogrel is used in pregnancy only if clearly needed. Animal studies have not shown harm, but human data are limited, and the bleeding risk around delivery needs careful planning. Always tell your doctor if you are pregnant or planning pregnancy so the risks and benefits can be weighed.

Lactation: It is not known whether clopidogrel passes into human breast milk. Breastfeeding is generally not recommended during treatment — discuss with your doctor whether to stop the medicine or stop breastfeeding based on how essential the drug is for you.

Store below 30°C in a cool, dry place away from direct sunlight and moisture. Keep in the original blister pack until use, and keep out of the reach of children. Do not use after the expiry date.