Meltix 500 mcg + 10 mg Tablet

Meltix is a tablet containing flupentixol and melitracen, an antipsychotic plus tricyclic antidepressant combination. It is used in adults for depressive states with anxiety, tension, low mood, or related psychosomatic symptoms when a clinician considers this combination appropriate.

Meltix 500 mcg + 10 mg tablet is manufactured and marketed by Navana Pharmaceuticals Ltd. in Bangladesh. It is a fixed combination of two medicines — flupentixol (a low-dose thioxanthene agent) and melitracen (a tricyclic antidepressant) — widely prescribed in Bangladesh for mixed anxiety and depression. Despite how commonly it is dispensed, it is a strictly prescription-only psychiatric medicine, not a casual remedy for daily stress or so-called gastric tension.

In low doses, flupentixol acts on dopamine and serotonin signalling to lift mood and ease anxiety, while melitracen increases the availability of noradrenaline and serotonin between nerve cells. Together they produce a combined anxiety-reducing and mood-brightening effect that typically becomes evident within the first weeks of regular, doctor-supervised use.

Doctors may prescribe Meltix for:

• Mixed anxiety and depression — persistent worry with low mood, poor enjoyment and disturbed sleep
• Psychosomatic complaints — real physical symptoms (palpitations, chest tightness, stomach discomfort, aches) driven by underlying anxiety or low mood, after medical causes have been checked
• Apathy, fatigue and tension states in selected patients, including some menopausal mood symptoms

What it is not for: everyday stress, exam tension, ordinary gastric symptoms or sleep problems. Self-prescribing this combination — a common practice in Bangladesh — risks side effects, masking of real disease and long-term reliance on a tablet without treating the underlying condition.

ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Meltix 500 mcg + 10 mg Tablet. Use the dose your doctor prescribed and the instructions in the pack leaflet.

Possible side effects include:

• Common: restlessness or inner agitation, difficulty sleeping (especially if taken late in the day), dry mouth, dizziness, tremor, constipation, sweating, palpitations
• Less common: weight change, blurred vision, difficulty passing urine, reduced sexual function
• With long-term use: involuntary repetitive movements of the tongue, lips or face (tardive dyskinesia) — a potentially persistent problem that demands immediate medical review
• Serious (urgent): high fever with stiff muscles and confusion, fainting, irregular heartbeat, jaundice, severe allergic reaction

Report new movement symptoms, palpitations or marked agitation to your doctor promptly rather than adjusting the dose yourself.

Treat Meltix with the seriousness of any psychiatric medicine:

• Use it only on prescription — never self-start it for stress, insomnia or gastric-tension symptoms, however common that practice is
• It is unsuitable for indefinite unsupervised use; the need for it should be reviewed regularly, ideally by a psychiatrist
• Tell your doctor about heart disease, epilepsy, glaucoma, prostate enlargement, thyroid disease, liver or kidney problems and diabetes
• Avoid alcohol and sedatives, which worsen drowsiness and dizziness
• Be careful driving or operating machinery until you know its effect on you
• Elderly people need lower doses and closer observation
• Never stop abruptly after prolonged use — ask for a tapering plan

Meltix can interact significantly with:

• MAO inhibitors — must never be combined; a 14-day gap is required
• Other antidepressants (SSRIs such as escitalopram, SNRIs) — additive serotonin and heart-rhythm effects; combine only under psychiatric supervision
• Sedatives, sleeping pills, strong painkillers and alcohol — increased drowsiness and impaired alertness
• Blood-pressure medicines — effects may be reduced or exaggerated; dizziness on standing can worsen
• QT-prolonging medicines (certain antibiotics, antifungals, antiarrhythmics) — heart-rhythm risk
• Anticholinergic drugs — added dry mouth, constipation, urinary difficulty and blurred vision

Give your doctor a complete medicine list before starting.

Meltix must not be used in:

• Recent heart attack (myocardial infarction) or significant heart-rhythm disorders, including heart block
• Mania or markedly excited, agitated states — it can worsen them
• Concurrent or recent (within 14 days) MAO-inhibitor treatment
• Untreated narrow-angle glaucoma or urinary retention
• Severe liver disease
• Acute intoxication with alcohol, sedatives or opioids
• Known allergy to flupentixol, melitracen or related compounds
• Children and adolescents

People with epilepsy, Parkinsonism, prostate enlargement or significant heart disease need specialist assessment before this combination is considered at all.

Pregnancy: This combination is generally not recommended during pregnancy. The tricyclic and antipsychotic components, particularly near delivery, can cause temporary problems in the newborn, including jitteriness, feeding difficulty and withdrawal-like symptoms. If you take Meltix and become pregnant — or are planning to — consult your doctor promptly; treatment will be reviewed and switched or tapered appropriately rather than stopped abruptly.

Breastfeeding: Both components pass into breast milk in small amounts, and the combination is usually avoided during breastfeeding. If treatment for anxiety-depression is needed while nursing, the doctor will usually select a better-studied single medicine with an established safety record instead.

Store Meltix in its original pack below 30°C, away from light, heat and moisture, and never in damp bathrooms. Keep it strictly out of the reach of children — tricyclic-containing tablets are particularly dangerous if a child swallows them. Because this combination is so widely self-medicated in Bangladesh, do not share your tablets with relatives or neighbours for their tension or gastric complaints, and do not stockpile old strips for future use. Check expiry dates, discard damaged tablets and dispose of leftover medicine safely.