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Injection

Demoxiclav 500 mg + 100 mg Injection

Generic: Amoxicillin + Clavulanic Acid

Manufacturer: Drug International Ltd.

Therapeutic class: Penicillin + beta-lactamase inhibitor combination antibiotic

What is Demoxiclav used for?

Demoxiclav (Injection) contains Amoxicillin + Clavulanic Acid 500 mg + 100 mg and is made by Drug International Ltd. Therapeutic class: Penicillin + beta-lactamase inhibitor combination antibiotic.

What is Demoxiclav?

Demoxiclav 500 mg + 100 mg Injection contains amoxicillin with clavulanic acid, a penicillin antibiotic combination. It is used for susceptible bacterial infections when injectable treatment is needed, such as some respiratory, urinary, skin, soft tissue, and abdominal infections.

Demoxiclav 500 mg + 100 mg injection by Drug International Ltd. contains Amoxicillin + Clavulanic Acid, a combination antibiotic that pairs a penicillin with a beta-lactamase inhibitor. It is used for bacterial infections that may resist plain amoxicillin, including stubborn chest, sinus, ear, urinary, dental, and skin or soft-tissue infections. Demoxiclav is a prescription-only medicine and must be taken exactly as a registered doctor directs.

The amoxicillin part destroys bacteria by breaking down their protective cell wall. Many bacteria fight back by producing an enzyme called beta-lactamase that disables ordinary penicillins; the clavulanic acid in Amoxicillin + Clavulanic Acid blocks this enzyme, allowing the amoxicillin to work against a wider range of resistant bacteria.

Indications

  • Recurrent or resistant ear, nose, and sinus infections
  • Chest infections including some pneumonias and bronchitis flare-ups
  • Urinary tract infections
  • Dental abscesses and gum infections
  • Skin, soft-tissue, and animal/human bite wound infections

Dosage & Administration

ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Demoxiclav 500 mg + 100 mg Injection. Use the dose your doctor prescribed and the instructions in the pack leaflet.

Side Effects

Side effects are similar to amoxicillin but stomach upset is more common because of the clavulanic acid. They include:

  • Diarrhoea (quite common), nausea, and vomiting
  • Indigestion or abdominal pain
  • Mild skin rash or itching
  • Oral or vaginal thrush with longer courses

Rarely, Amoxicillin + Clavulanic Acid can affect the liver, causing yellowing of the skin or eyes and dark urine. Seek urgent care for severe allergic reactions, persistent or bloody diarrhoea, or signs of liver trouble.

Precautions & Warnings

Demoxiclav is a prescription-only antibiotic — never self-medicate. Use it only when a registered doctor prescribes it for your specific infection, and never share it or buy it on your own. Always complete the full course even after you feel well; stopping early lets resistant bacteria survive and the illness return more stubbornly.

Tell your doctor about any penicillin allergy or past liver problems, especially previous jaundice with this medicine. Antibiotic resistance is a serious national crisis in Bangladesh, and misuse of broad combinations like Amoxicillin + Clavulanic Acid accelerates it — reserve it strictly for when a doctor judges it necessary.

Drug Interactions

Inform your doctor about every medicine you take. Important interactions with Amoxicillin + Clavulanic Acid include:

  • Warfarin and other blood thinners — bleeding risk may increase
  • Methotrexate — its toxicity can rise
  • Allopurinol — greater chance of skin rash
  • Probenecid — should not be taken together
  • Oral typhoid vaccine and some other antibiotics

Contraindications

Do not take Demoxiclav if you:

  • Are allergic to penicillins, clavulanic acid, or cephalosporins
  • Have had jaundice or liver problems caused by this combination before

Use with caution in people with kidney or liver disease and in glandular fever, where it can cause a rash. Your doctor will weigh these factors before prescribing Demoxiclav.

Pregnancy & Lactation

Amoxicillin + Clavulanic Acid is usually considered acceptable in pregnancy when clearly needed, but should be taken only under medical supervision. Let your doctor know if you are pregnant or planning to be, so the safest option can be chosen.

Small amounts pass into breast milk and are generally regarded as compatible with breastfeeding, though the baby may develop loose stools or thrush. Always mention breastfeeding so your doctor can guide you.

Storage Conditions

Store as printed on the pack and keep out of the reach of children.

Frequently Asked Questions

How is Demoxiclav different from ordinary amoxicillin?

Demoxiclav contains amoxicillin plus clavulanic acid. Many bacteria produce an enzyme (beta-lactamase) that destroys plain amoxicillin before it can work; the added clavulanic acid blocks that enzyme, so Demoxiclav can treat infections that ordinary amoxicillin cannot. This makes it useful for tougher or recurrent infections, but it is not automatically "better" for every case. Your doctor chooses between them based on the likely bacteria. Using this stronger combination unnecessarily speeds up resistance, so take it only when specifically prescribed.

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