Injection
Demoxiclav 1 gm + 200 mg Injection
Generic: Amoxicillin + Clavulanic Acid
Manufacturer: Drug International Ltd.
Therapeutic class: Penicillin + beta-lactamase inhibitor combination antibiotic
What is Demoxiclav used for?
Demoxiclav (Injection) contains Amoxicillin + Clavulanic Acid 1 gm + 200 mg and is made by Drug International Ltd. Therapeutic class: Penicillin + beta-lactamase inhibitor combination antibiotic.
What is Demoxiclav?
Demoxiclav 1 gm + 200 mg Injection contains amoxicillin with clavulanic acid, a penicillin antibiotic combined with a beta-lactamase inhibitor. It is used for bacterial infections where this combination is appropriate, including infections caused by susceptible beta-lactamase producing bacteria.
Demoxiclav 1 gm + 200 mg injection by Drug International Ltd. contains Amoxicillin + Clavulanic Acid, a combination antibiotic that pairs a penicillin with a beta-lactamase inhibitor. It is used for bacterial infections that may resist plain amoxicillin, including stubborn chest, sinus, ear, urinary, dental, and skin or soft-tissue infections. Demoxiclav is a prescription-only medicine and must be taken exactly as a registered doctor directs.
The amoxicillin part destroys bacteria by breaking down their protective cell wall. Many bacteria fight back by producing an enzyme called beta-lactamase that disables ordinary penicillins; the clavulanic acid in Amoxicillin + Clavulanic Acid blocks this enzyme, allowing the amoxicillin to work against a wider range of resistant bacteria.
Indications
- Recurrent or resistant ear, nose, and sinus infections
- Chest infections including some pneumonias and bronchitis flare-ups
- Urinary tract infections
- Dental abscesses and gum infections
- Skin, soft-tissue, and animal/human bite wound infections
Dosage & Administration
ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Demoxiclav 1 gm + 200 mg Injection. Use the dose your doctor prescribed and the instructions in the pack leaflet.
Side Effects
Side effects are similar to amoxicillin but stomach upset is more common because of the clavulanic acid. They include:
- Diarrhoea (quite common), nausea, and vomiting
- Indigestion or abdominal pain
- Mild skin rash or itching
- Oral or vaginal thrush with longer courses
Rarely, Amoxicillin + Clavulanic Acid can affect the liver, causing yellowing of the skin or eyes and dark urine. Seek urgent care for severe allergic reactions, persistent or bloody diarrhoea, or signs of liver trouble.
Precautions & Warnings
Demoxiclav is a prescription-only antibiotic — never self-medicate. Use it only when a registered doctor prescribes it for your specific infection, and never share it or buy it on your own. Always complete the full course even after you feel well; stopping early lets resistant bacteria survive and the illness return more stubbornly.
Tell your doctor about any penicillin allergy or past liver problems, especially previous jaundice with this medicine. Antibiotic resistance is a serious national crisis in Bangladesh, and misuse of broad combinations like Amoxicillin + Clavulanic Acid accelerates it — reserve it strictly for when a doctor judges it necessary.
Drug Interactions
Inform your doctor about every medicine you take. Important interactions with Amoxicillin + Clavulanic Acid include:
- Warfarin and other blood thinners — bleeding risk may increase
- Methotrexate — its toxicity can rise
- Allopurinol — greater chance of skin rash
- Probenecid — should not be taken together
- Oral typhoid vaccine and some other antibiotics
Contraindications
Do not take Demoxiclav if you:
- Are allergic to penicillins, clavulanic acid, or cephalosporins
- Have had jaundice or liver problems caused by this combination before
Use with caution in people with kidney or liver disease and in glandular fever, where it can cause a rash. Your doctor will weigh these factors before prescribing Demoxiclav.
Pregnancy & Lactation
Amoxicillin + Clavulanic Acid is usually considered acceptable in pregnancy when clearly needed, but should be taken only under medical supervision. Let your doctor know if you are pregnant or planning to be, so the safest option can be chosen.
Small amounts pass into breast milk and are generally regarded as compatible with breastfeeding, though the baby may develop loose stools or thrush. Always mention breastfeeding so your doctor can guide you.
Storage Conditions
Store as printed on the pack and keep out of the reach of children.