Tablet
Clavulin 375 250 mg + 125 mg Tablet
Generic: Amoxicillin + Clavulanic Acid
Manufacturer: Euro Pharma Ltd.
Therapeutic class: Penicillin + beta-lactamase inhibitor combination antibiotic
What is Clavulin 375 used for?
Clavulin 375 (Tablet) contains Amoxicillin + Clavulanic Acid 250 mg + 125 mg and is made by Euro Pharma Ltd. Therapeutic class: Penicillin + beta-lactamase inhibitor combination antibiotic.
What is Clavulin 375?
Clavulin 375 is a tablet containing amoxicillin 250 mg with clavulanic acid 125 mg, a penicillin-type antibiotic combination. It is used to treat bacterial infections caused by susceptible organisms, such as infections of the respiratory tract, urinary tract, skin, soft tissue, or dental area.
Clavulin 375 250 mg + 125 mg tablet by Euro Pharma Ltd. contains Amoxicillin + Clavulanic Acid, a combination antibiotic that pairs a penicillin with a beta-lactamase inhibitor. It is used for bacterial infections that may resist plain amoxicillin, including stubborn chest, sinus, ear, urinary, dental, and skin or soft-tissue infections. Clavulin 375 is a prescription-only medicine and must be taken exactly as a registered doctor directs.
The amoxicillin part destroys bacteria by breaking down their protective cell wall. Many bacteria fight back by producing an enzyme called beta-lactamase that disables ordinary penicillins; the clavulanic acid in Amoxicillin + Clavulanic Acid blocks this enzyme, allowing the amoxicillin to work against a wider range of resistant bacteria.
Indications
- Recurrent or resistant ear, nose, and sinus infections
- Chest infections including some pneumonias and bronchitis flare-ups
- Urinary tract infections
- Dental abscesses and gum infections
- Skin, soft-tissue, and animal/human bite wound infections
Dosage & Administration
ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Clavulin 375 250 mg + 125 mg Tablet. Use the dose your doctor prescribed and the instructions in the pack leaflet.
Side Effects
Side effects are similar to amoxicillin but stomach upset is more common because of the clavulanic acid. They include:
- Diarrhoea (quite common), nausea, and vomiting
- Indigestion or abdominal pain
- Mild skin rash or itching
- Oral or vaginal thrush with longer courses
Rarely, Amoxicillin + Clavulanic Acid can affect the liver, causing yellowing of the skin or eyes and dark urine. Seek urgent care for severe allergic reactions, persistent or bloody diarrhoea, or signs of liver trouble.
Precautions & Warnings
Clavulin 375 is a prescription-only antibiotic — never self-medicate. Use it only when a registered doctor prescribes it for your specific infection, and never share it or buy it on your own. Always complete the full course even after you feel well; stopping early lets resistant bacteria survive and the illness return more stubbornly.
Tell your doctor about any penicillin allergy or past liver problems, especially previous jaundice with this medicine. Antibiotic resistance is a serious national crisis in Bangladesh, and misuse of broad combinations like Amoxicillin + Clavulanic Acid accelerates it — reserve it strictly for when a doctor judges it necessary.
Drug Interactions
Inform your doctor about every medicine you take. Important interactions with Amoxicillin + Clavulanic Acid include:
- Warfarin and other blood thinners — bleeding risk may increase
- Methotrexate — its toxicity can rise
- Allopurinol — greater chance of skin rash
- Probenecid — should not be taken together
- Oral typhoid vaccine and some other antibiotics
Contraindications
Do not take Clavulin 375 if you:
- Are allergic to penicillins, clavulanic acid, or cephalosporins
- Have had jaundice or liver problems caused by this combination before
Use with caution in people with kidney or liver disease and in glandular fever, where it can cause a rash. Your doctor will weigh these factors before prescribing Clavulin 375.
Pregnancy & Lactation
Amoxicillin + Clavulanic Acid is usually considered acceptable in pregnancy when clearly needed, but should be taken only under medical supervision. Let your doctor know if you are pregnant or planning to be, so the safest option can be chosen.
Small amounts pass into breast milk and are generally regarded as compatible with breastfeeding, though the baby may develop loose stools or thrush. Always mention breastfeeding so your doctor can guide you.
Storage Conditions
Store as printed on the pack and keep out of the reach of children.