Tablet
Apzol 400 mg Tablet
Generic: Albendazole
Manufacturer: Apex Pharma Ltd.
Therapeutic class: Anthelmintic (Benzimidazole)
What is Apzol used for?
Apzol (Tablet) contains Albendazole 400 mg and is made by Apex Pharma Ltd. Therapeutic class: Anthelmintic (Benzimidazole).
What is Apzol?
Apzol 400 mg Tablet contains albendazole, a benzimidazole anthelmintic medicine from Apex Pharma Ltd. It is used to treat infections caused by parasitic worms, including common intestinal worms, as advised by a healthcare professional.
Apzol 400 mg tablet is a broad-spectrum deworming (anthelmintic) medicine from Apex Pharma Ltd. containing Albendazole. It is the most commonly used worm medicine in Bangladesh, effective against roundworm, hookworm, whipworm, pinworm (threadworm), and several other intestinal parasites. It is also used in higher, longer doses for tissue infections such as hydatid disease and neurocysticercosis under specialist care.
Albendazole works by blocking the worms' ability to absorb glucose, their main energy source. Starved of energy, the worms become paralysed, die, and are passed out of the body in the stool. Because worm infections spread easily within households — through soil, unwashed hands, and contaminated food — treating all family members at the same time gives the best result.
Indications
- Roundworm (Ascaris) infection
- Hookworm and whipworm infection
- Pinworm/threadworm (Enterobius) infection
- Strongyloides and mixed intestinal worm infections
- Giardiasis in children (as advised by a doctor)
- Hydatid disease and neurocysticercosis (specialist use)
Dosage & Administration
ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Apzol 400 mg Tablet. Use the dose your doctor prescribed and the instructions in the pack leaflet.
Side Effects
With single-dose use, albendazole rarely causes problems. Some people experience mild stomach pain, nausea, diarrhoea, headache, or dizziness, which settle on their own. When worms die in heavy infections, temporary abdominal discomfort can occur. High-dose, long-term treatment for tissue infections may cause liver enzyme changes, hair thinning, fever, or low blood counts — these patients need regular blood monitoring. Seek medical help for rash, jaundice, or unusual bruising or bleeding.
Precautions & Warnings
Deworming works best alongside hygiene: wash hands with soap before eating and after using the toilet, trim nails, wash vegetables well, and wear sandals outdoors to prevent reinfection. Treat all household members on the same day. Use with caution in liver disease; prolonged courses require liver function and blood count monitoring. Women of childbearing age should ensure they are not pregnant before taking albendazole and avoid pregnancy during and shortly after high-dose treatment.
Drug Interactions
For routine single-dose deworming, significant drug interactions are uncommon. In prolonged high-dose therapy, dexamethasone, praziquantel, and cimetidine raise albendazole levels, while the anti-epileptics carbamazepine, phenytoin, and phenobarbital lower them. Grapefruit juice may also increase absorption. Tell your doctor about all medicines you take if you are prescribed a long course of albendazole.
Contraindications
Albendazole must not be taken by people with known hypersensitivity to albendazole or other benzimidazoles (such as mebendazole). It is contraindicated in pregnancy, particularly the first trimester. It is generally not given to children under 1 year of age. In known retinal cysticercosis, treatment requires specialist assessment first, as dying parasites can damage the eye.
Pregnancy & Lactation
Pregnancy: Albendazole is contraindicated in pregnancy, especially during the first trimester, due to the risk of harm to the developing baby. Women should rule out pregnancy before taking it. Where deworming is needed in pregnancy, health programmes only give it after the first trimester under medical guidance. Lactation: A single dose is generally considered acceptable while breastfeeding, but consult your doctor first.
Storage Conditions
Store as printed on the pack and keep out of the reach of children.