Acimec 10 mg/ml Injection

An injectable form of the avermectin antiparasitic ivermectin, Acimec injection is presented at 10 mg/ml. Ivermectin is used to control parasitic infestations by acting on the nervous system of the parasites to paralyse and eliminate them.

Acimec 10 mg/ml injection is an antiparasitic medicine from Advanced Chemical Industries Limited containing Ivermectin. In Bangladesh it is most often prescribed for scabies — especially when creams have failed or many family members are affected — and for worm infections such as strongyloidiasis and filariasis. It is also used for head lice resistant to usual treatments. Acimec should only be taken when a doctor has confirmed the diagnosis.

Ivermectin works by binding to special chloride channels found in the nerve and muscle cells of parasites. This paralyses the mites or worms so they die and are cleared by the body. Because these channels work differently in humans, the medicine is selective against parasites at prescribed doses, making it an effective oral option for scabies and several worm diseases.

• Scabies, including crusted scabies and household outbreaks
• Strongyloidiasis (threadworm of the gut)
• Lymphatic filariasis (as part of programme treatment)
• Onchocerciasis (river blindness)
• Head lice resistant to topical treatment
• Cutaneous larva migrans (as advised by a doctor)

ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Acimec 10 mg/ml Injection. Use the dose your doctor prescribed and the instructions in the pack leaflet.

Ivermectin is usually well tolerated as a single dose. Possible side effects include dizziness, nausea, diarrhoea, stomach pain, headache, and drowsiness. In scabies, itching may temporarily worsen for a few days as mites die — this is expected and not treatment failure. When many parasites die at once (especially in filariasis), fever, rash, joint pain, and swollen glands can occur. Seek urgent care for severe rash, swelling of face or throat, confusion, or vision problems.

For scabies, treat all household members and close contacts on the same day, wash bedding and clothes in hot water, and dry them in the sun to prevent reinfestation. Itching may continue for 2–4 weeks after successful treatment; do not keep repeating doses without a doctor's advice. Use caution in liver disease, in severe debility, and in patients from areas where Loa loa infection occurs. The safety of ivermectin in children under 15 kg is not established. Avoid driving if you feel dizzy or drowsy after the dose.

Ivermectin may increase the effect of warfarin, so blood clotting (INR) may need closer monitoring. Drugs that affect the P-glycoprotein transporter or liver enzyme CYP3A4 — such as ketoconazole, itraconazole, ritonavir, and verapamil — can raise ivermectin levels and side effects. Alcohol may increase absorption and adverse effects, so avoid it around the time of dosing. Tell your doctor about all medicines, including herbal products, before taking ivermectin.

Ivermectin must not be taken by people with known hypersensitivity to it. It is not recommended in children weighing under 15 kg, in pregnancy, or during the first week of breastfeeding unless a doctor decides the benefit outweighs the risk. Special caution applies in patients with conditions that weaken the blood–brain barrier, such as severe meningitis or trypanosomiasis.

Pregnancy: Ivermectin is generally avoided in pregnancy because safety has not been established; treatment for scabies in pregnant women is usually with permethrin cream instead. Lactation: Small amounts pass into breast milk. Many guidelines allow use during established breastfeeding when clearly needed, but it is best avoided in the first week after birth. Always consult your doctor before use if pregnant or breastfeeding.

Store as printed on the pack and keep out of the reach of children.