Acifix 10 mg Tablet

Acifix 10 is a rabeprazole sodium 10 mg tablet from Beximco Pharmaceuticals Ltd., belonging to the proton pump inhibitor class. It is used to reduce stomach acid in conditions such as gastro-oesophageal reflux disease, erosive oesophagitis, and peptic ulcer disease.

Acifix 10 10 mg tablet is a product of Beximco Pharmaceuticals Ltd. containing Rabeprazole Sodium, a widely used proton pump inhibitor (PPI). It reduces the amount of acid the stomach produces and is prescribed for acid reflux (GERD), peptic ulcers, and other acid-related disorders. Acifix 10 is usually taken once daily, most often before breakfast.

Rabeprazole Sodium works by irreversibly blocking the hydrogen-potassium ATPase enzyme — the "proton pump" — in the acid-producing cells of the stomach wall. With less acid in the stomach, ulcers get a chance to heal, reflux symptoms such as heartburn ease, and the food pipe is protected from further acid damage. Rabeprazole is activated quickly at the pump, which contributes to its relatively prompt onset of acid suppression.

Rabeprazole Sodium is indicated for:

• Gastro-oesophageal reflux disease (GERD) — heartburn, regurgitation and erosive oesophagitis
• Gastric and duodenal ulcers — healing of active ulcers
• Helicobacter pylori eradication — combined with antibiotics
• NSAID-associated ulcers — treatment and prevention in at-risk patients
• Zollinger-Ellison syndrome and other conditions with excessive acid secretion

Your registered doctor will confirm the diagnosis and decide whether rabeprazole is the right choice and for how long it should be taken.

ChamberBD shows dosing only from the approved product label, with its source named, and no label is on file for Acifix 10 mg Tablet. Use the dose your doctor prescribed and the instructions in the pack leaflet.

Most people tolerate Rabeprazole Sodium well. Reported side effects include:

• Common: headache, diarrhoea, nausea, abdominal pain, flatulence, dizziness
• Less common: constipation, dry mouth, rash, muscle or joint aches, sleep disturbance
• Rare/long-term: low magnesium or sodium, vitamin B12 deficiency, bone fracture risk with prolonged use, gut infections, and rarely kidney inflammation (interstitial nephritis)

Stop the medicine and seek urgent care if you notice severe skin reactions, swelling of the face or throat, breathing difficulty, or persistent watery diarrhoea.

Take these precautions with Rabeprazole Sodium:

• Inform your doctor of any liver disease, kidney problems, osteoporosis or low magnesium
• Alarm symptoms — unintentional weight loss, repeated vomiting, difficulty swallowing, blood in vomit or stool — should be investigated before or alongside treatment
• Long-term users may need periodic review and occasionally magnesium or B12 checks
• PPIs can slightly raise the risk of gut infections because stomach acid is a natural barrier
• Take the full prescribed course; stopping early may allow symptoms or ulcers to return

Important interactions of Rabeprazole Sodium include:

• Acid-dependent drugs: reduced absorption of ketoconazole, itraconazole, iron, and HIV drugs such as atazanavir and rilpivirine
• Warfarin: possible INR changes; monitoring advised
• Methotrexate: levels may rise, especially with high-dose therapy
• Digoxin: absorption may increase slightly
• Clopidogrel: rabeprazole appears to interact less than omeprazole, but inform your doctor if you take antiplatelet therapy

Share a complete list of your medicines, supplements and herbal remedies with your doctor and pharmacist before starting Acifix 10.

Do not use Rabeprazole Sodium if any of the following apply:

• Known allergy to rabeprazole, substituted benzimidazoles (other PPIs), or any excipient of the tablet
• Concurrent use with rilpivirine-containing products
• History of a serious PPI-induced reaction such as acute interstitial nephritis or severe cutaneous reaction

Caution is required in pregnancy, breastfeeding and severe liver impairment — in these situations the medicine should only be used when a doctor judges the benefit to outweigh the risk.

Pregnancy: Safety data for rabeprazole in human pregnancy are limited. It should be used during pregnancy only if clearly needed and prescribed by a doctor, who may prefer alternatives with more established pregnancy safety records.

Lactation: It is not known whether rabeprazole is excreted in human breast milk, although it appears in animal milk. Because a risk to the nursing infant cannot be excluded, a decision should be made with your doctor on whether to discontinue nursing or the drug, considering how important the treatment is for the mother.

Store below 30°C in a dry place, protected from light and moisture. Keep the tablet in the original packaging until use, as the enteric coating is sensitive to humidity. Keep out of the reach and sight of children. Never use the medicine after its expiry date; return expired medicines to a pharmacy where possible.